Journal Articles

Access peer-reviewed journal articles sponsored by Dyne Therapeutics offering insights into the FORCE™ platform.

The FORCE™ platform, zeleciment-basivarsen (z-basivarsen, also known as DYNE-101), zeleciment-rostudirsen (z-rostudirsen, also known as DYNE-251), DYNE-302, and DYNE-401 are investigational or otherwise in development and have not been approved as safe or effective by the US FDA, EMA or any other regulatory authority.

FORCE platform overcomes barriers of oligonucleotide delivery to muscle and corrects myotonic dystrophy features in preclinical models

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Patient engagement in clinical trial design for rare neuromuscular disorders: impact on the DELIVER and ACHIEVE clinical trials

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Enhanced exon skipping and prolonged dystrophin restoration achieved by TfR1-targeted delivery of antisense oligonucleotide using FORCE conjugation in mdx mice

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Changes in RNA splicing as a surrogate endpoint for Myotonic Dystrophy Type 1 (DM1) clinical trials

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Reaching the CNS with therapeutic oligonucleotides via TfR1: navigating delivery and distribution challenges

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Clinical and healthcare burden of myotonic dystrophy type 1 (DM1) in the United States: a claims-based study

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